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IGF-1-LR3_1mg

IGF-1LR3 1mg

49 customer reviews

$56.00

IGF-1LR3 1mg

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PLEASE NOTE: This product is intended for research use only! This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic. See FDA disclaimers bottom of page.

Description

IGF-1LR3: Backgrounder

Insulin-like Growth Factor 1 Long Arg3 (IGF-1LR3) is a synthetic peptide analog of the naturally occurring IGF-1, a hormone closely related to insulin. IGF-1 plays a key role in growth, cell development, and tissue repair. The LR3 modification significantly enhances its stability and biological activity, making it widely used in research related to muscle growth, regeneration, and metabolic studies.

What Makes IGF-1 LR3 Different?

IGF-1LR3 is a modified version of native IGF-1 with two key changes:

  • A substitution of arginine at position 3 (hence “Arg3”)
  • An additional 13 amino acids added to the N-terminus

These alterations make LR3:

  • More resistant to binding proteins that would normally inactivate IGF-1
  • Approximately 2–3x more potent than regular IGF-1
  • Possess a longer half-life (around 20–30 hours vs. 20–30 minutes for native IGF-1)

Mechanism of Action

IGF-1LR3 mimics the effects of insulin and growth hormone by activating the IGF-1 receptor (IGF1R) in muscle and other tissues. This triggers downstream pathways (notably the PI3K-AKT-mTOR pathway) that:

  • Stimulate protein synthesis
  • Inhibit protein breakdown
  • Promote cell survival and growth

Research Applications

While IGF-1LR3 is not FDA-approved for human use, it is used in laboratory studies exploring:

  • Muscle hypertrophy and repair
  • Neurological regeneration
  • Anti-aging and metabolic regulation
  • Diabetes and insulin sensitivity models

Important Considerations

  • Not for human consumption: IGF-1LR3 is intended for research use only.
  • Potent biological effects: Improper use may lead to adverse effects like hypoglycemia, organomegaly, or imbalanced growth signals.
PLEASE NOTE! THIS PRODUCT IS INTENDED FOR RESEARCH USE ONLY!
  • All products provided by Sigma Labs are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration. The products offered on this platform are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any diseases or medical conditions.
  • Sigma Labs is a chemical supplier. Sigma Labs is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. (Merchant Name) is not an outsourcing facility as defined under 503B of the Federal Food, Drug, and Cosmetic act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.
  • The products offered on this platform are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any diseases or medical conditions.

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Please Be Advised:

All research peptides from Sigmalabsus.com are strictly for in-vitro research and are not intended for use in humans or animals. You must be at least 21 years of age and agree with the Sigmalabsus.com “No Tolerance Policy,” detailed here: Zero Tolerance Policy. Any products purchased through this website will not be consumed by humans or animals, nor will they be used as food additives, drugs, or household chemicals.

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All products showcased on this website are intended solely for Research and Development purposes. These products are strictly not intended for any form of human consumption. Please note that the statements made on this website have not undergone evaluation by the US Food and Drug Administration. Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.

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