Description
PT-141 (Bremelanotide) Peptide – Lyophilized Research Compound
Overview of PT-141
PT-141 peptide, also known as Bremelanotide, is a synthetic cyclic peptide analog referenced in peptide chemistry and molecular signaling research literature. In laboratory environments, this compound is commonly examined in experimental models involving melanocortin receptor interactions, molecular signaling pathways, and peptide structure analysis.
PT-141 peptide is structurally related to melanocortin peptides derived from the α-MSH (alpha-melanocyte stimulating hormone) peptide family. Because of its defined cyclic peptide structure and reproducible synthesis profile, PT-141 is frequently included in laboratory research examining peptide signaling behavior and receptor interaction mechanisms.
Scientific Research Context
In biochemical and molecular research environments, PT-141 is referenced in studies examining melanocortin receptor signaling pathways and peptide interaction systems. Laboratory investigations involving this peptide may include:
- Peptide receptor interaction studies
- Molecular signaling pathway analysis
- Comparative peptide stability research
- Structural peptide characterization
- Analytical evaluation of cyclic peptide analogs
Presence in Scientific Literature
PT-141 appears in scientific publications discussing melanocortin receptor signaling and peptide molecular interactions. In laboratory environments it may serve as a reference compound when studying receptor-binding mechanisms and peptide signaling pathways.
Lyophilized PT-141 Preparation
Freeze-Dried Peptide Format
PT-141 research compounds are typically supplied in a lyophilized (freeze-dried) format. Lyophilization removes solvent under controlled vacuum and temperature conditions, producing a stable dry peptide preparation suitable for laboratory storage and transport.
Visual Characteristics
Depending on manufacturing and freeze-drying parameters, lyophilized PT-141 may appear as:
- Fine white peptide powder
- Porous lyophilized cake
- Compact peptide layer adhered to the vial surface
Minor visual variations between vials are normal and typically reflect small differences in lyophilization conditions during production.
Chemical Characteristics of PT-141
Key Molecular Attributes
- Compound Type: Synthetic cyclic peptide analog
- Peptide Class: Melanocortin receptor peptide analog
- Peptide Length: 7 amino acids
- Molecular Formula: C50H68N14O9
- Molecular Weight: ~1025 g/mol
- CAS Number: 189691-06-3
- Appearance: White lyophilized peptide preparation
Formulation Stability
Laboratory peptide preparations of PT-141 may contain stabilizing excipients designed to maintain peptide integrity during storage and lyophilization. These stabilizers are commonly used in peptide manufacturing and research reagent preparation.
Reconstitution Characteristics
Dissolution Behavior in Laboratory Settings
When reconstituting lyophilized PT-141 peptide for laboratory use, solvent composition may influence dissolution characteristics and experimental consistency.
Solvent Considerations
Solvents containing preservatives or buffering agents may interact with peptide formulation components. For controlled laboratory preparation, purified laboratory-grade water is commonly used when dissolving peptide compounds.
PT-141 in Laboratory Research
PT-141 has been referenced in scientific literature involving melanocortin receptor signaling pathways and peptide interaction research. In controlled laboratory environments, the peptide may be incorporated into experimental models examining:
- Peptide receptor binding characteristics
- Molecular signaling pathway modeling
- Comparative peptide stability studies
- Structural peptide analysis
- Analytical characterization of melanocortin peptides
Storage & Handling
Recommended Storage Conditions
- Store refrigerated at 2–8°C unless otherwise specified
- Protect peptide material from moisture and excessive light
- Keep vials sealed until laboratory use
- Avoid repeated freeze-thaw cycles after reconstitution
Laboratory Handling Practices
PT-141 peptide should be handled using appropriate sterile laboratory techniques and standard research protocols to maintain sample integrity and experimental reliability.
Frequently Asked Questions About PT-141
What is PT-141?
PT-141 (Bremelanotide) is a synthetic cyclic peptide analog derived from melanocortin peptides and referenced in peptide signaling and receptor interaction research.
How is PT-141 supplied for research?
PT-141 research compounds are typically supplied as lyophilized powder in sealed laboratory vials to maintain stability during storage and transportation.
Why are peptides supplied in lyophilized form?
Lyophilization removes water from peptide solutions under controlled vacuum conditions, producing a stable dry peptide preparation suitable for long-term storage and laboratory preparation.
